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Whats New 2004

 

Soy might not be a good idea for men.

  The drama surrounding soy has seesawed in recent times.  First we thought it was good for the heart via lowering cholesterol, protected the prostate and helped preserve bone density.  Then in the year 2000 the tofu study was released, which generated massive consternation, showing a dose-dependent connection between the consumption of this substance and the subsequent development of brain atrophy and dementia in Hawaiian males.  Subsequent to that evidence from the World conference on Soy revealed that soy consumption actually improved memory.  Now a summary article in the Journal of Anti-aging Medicine, Volume 6, Number 4 2003 indicates that in tissue culture the soy phytoestrogen genistein has the ability to suppress DNA synthesis and to repress brain derived neurotrophic factor as well as to increase glutamate toxicity and peroxides or free radicals derived from glutamate.  In short soy blocks the formation of new brain cells and exposes those present to increasing levels of toxicity.  In 2003 experiments on male rats have confirmed soy’s tendency to put the brakes on brain derived neurotrophic factor in the hippocampus which is the memory centre as well as the cortex thereby suggesting that soy may cause brain atrophy in males.  Fascinatingly the opposite seems to happen to female rats suggesting that soy might be protective to female brains.  What is the poor hapless male to make of all of this?  Clearly we need more scientific evaluation of the pros and cons of this endlessly mystifying substance but until this is available I am advising males to consume less soy and to limit their weekly quota to 2—3 serves and to avoid soymilk. 



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