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Questions and Answers Segment

Your questions answered every 2 weeks. If you have a question for Dr Elstein, click here.


QUESTION 1: You say that cortisol causes leptin resistance.  I find that very interesting and I was wondering if you could direct me to research that demonstrates this.

Answer:  Cortisol is the stress hormone and there is evidence linking the over-secretion of this hormone both with insulin and leptin resistance which makes it more difficult to lose weight.   Leptin is the hormone which tells us to stop eating when we have had enough but once we start to put on weight this mechanism ceases to operate efficiently which compels us to eat even more.  If you go to the ‘Medline’ site, which you can access, via the Google search engine you will find studies that detail this process.  For example I have included excerpts from an abstract which explains this:  Clin Endocrinol (Oxf). 2000 Jan;52(1):107-12.The innate immune response and type 2 diabetes: evidence that leptin is associated with a stress-related (acute-phase) reaction.’
Pickup JC, Chusney GD, Mattock MB. ‘CONCLUSIONS: Serum leptin concentrations in type 2 diabetes are partly related to an acute-phase or stress response, independent of BMI and sex. The association of hyperleptinaemia with elevated serum cortisol provides a mechanism for leptin resistance in type 2 diabetes (glucocorticoids inhibit the central action of leptin). This study provides further support for the theory that type 2 diabetes is associated with chronic innate immune activation.’


QUESTION 2: I have read both your book, ‘Eternal Health’, and ‘Eat Right for your Blood Type’.  My questions are: in Eat Right for your Blood Type (I am O positive) it says that I should avoid cabbage and cauliflower and eat red meat. Firstly your book recommends that these vegetables contain essential vitamins and minerals to assist in all sort of things - what can I eat that will replace these and give the same effect?  It also recommends that I eat red meat (I prefer a vegetarian diet) - what do I substitute the meat with?

Answer:  You have to tailor this information to your needs.  There are many other vegetables to choose from such as spinach, broccoli and bok choy that can provide you with the essential vitamins and minerals.  If you elect not to consume red meat then white meat, fish, eggs, beans, nuts, and rice can provide you with your protein needs.  If you decide to follow the ‘Blood type diet’ then you have to see whether these suggestions fit in with the recommendations of this diet.


QUESTION 3:  I've purchased and wish to start taking Neurazest for tinnitus but am concerned with possible interactions with other pharmaceutical medications that I am taking for other conditions.  I'm taking OXYNORM, TRITACE, STILNOX and EZETROL.  Is Neurazest able to be taken in combination without any adverse affects?

Answer:  I could not find any evidence that Neurazest clashes with any of these medications.


QUESTION 4:   1.What is your opinion about Nutritional Supplementations?
2.Do you believe in the concept of 'Oxidative Stress'?
3.Do you believe that we need to supplement our diet with optimum level of NUTRIENTS rather than RDA(Recommended Dietary Allowance)?
4 Do you believe if we supply enough antioxidants to our body we can slow down the process of aging?

Answer:  Unquestionably we need supplementary antioxidants to optimize our health and this may slow down the aging process and contribute to the prevention of the diseases of aging such as Alzheimer’s dementia, Parkinson’s disease, cancer and heart disease which are all linked to the excessive accumulation of oxidative stress or free radical damage.  The Recommended Dietary Allowance recommendation is only intended to prevent deficiency diseases rather than provide us with nutrients levels that will maximize our functioning and therefore these suggestions are woefully inadequate.


QUESTION 5: After 12 years of remission if have Grave’s disease again.  I have lost my sex drive and wonder whether this is linked?

Answer:  Once your thyroid hormones are out of balance this can certainly impact your sexual function although there are many other factors to evaluate such as the levels of your other hormones, your nutritional status, the quality of your relationship and your stress levels to name but a few.  You would need to review these with your doctor.


QUESTION 6: I have been diagnosed with inflammation of the lower oesophagus which first occurred in June of 2004.  Xanax and Nexium were prescribed.  In January of this year I developed a condition whereby my tongue felt hot, as if I could breath fire.  Is this also a symptom of heartburn, or acid reflux, or Barretts oesophagitis?  Nexium does not seem to help much.  What foods, or herbs could I be consuming as alternates to prescriptions?

Answer:  The experience of a hot tongue might be related to acid reflux or be associated with B vitamin or iron deficiencies as well as other possibilities and I would strongly recommend that you have this reviewed by your doctor.  There are natural remedies such as slippery elm which can be used to manage inflammation.  I have also found that exploring gluten intolerance and yeast overgrowth and treating either or both of these if they are present can lead to positive outcomes.


QUESTION 7:  I was diagnosed with primary vestibulitis some time ago, though it's believed I have had it for years.  I only discovered it upon first attempt at intercourse when I married.  My husband and I have tried a variety of treatments and are now considering surgery.  We cannot have intercourse due to the pain and it's very sad to live in a sex-less marriage.  Recently I was also diagnosed as a celiac with a gluten intolerance.  Thus, I will begin a gluten-free diet.  Have you ever heard of a connection between celiac sprue and vestibulitis or gastrointestinal disorders related to vestibulitis?  I'm wondering if a gluten-free diet might also affect my chronic vaginal yeast problems and ultimately my vestibulitis as well. 

Answer:  I could not find a connection between gluten intolerance and vestibulitis which is a painful vaginal condition.  This does not mean that avoiding gluten won’t be helpful.  Chronic vaginal yeast infection can be associated with gluten intolerance.  You might find that treating yeast overgrowth aggressively with a yeast-free diet as well as probiotics such as acidophilus and bifidus and herbal compounds including oregano, pau d’arco, olive leaf extract and others might lead to considerable improvements.  Your partner should be on a similar programme.


QUESTION 8: I am concerned about some hair loss I have been having.  I had a baby in May of last year, then was told I had cervical cancer. I had a hysteroscopy with a DNC in July. Then had a hysterectomy in Sept. I received a good pap test so I was told I did not need in further treatment except regular pap test every 3 to 4 months for awhile. So why is my hair falling out?

Answer:  A gluten intolerance, nutritional deficiencies, inadequate production of thyroid hormone, excessive accumulation of stress, elevated levels of male hormones including testosterone and dihydrotestosterone which might be linked to a condition known as insulin resistance and obesity as well as immune dysfunction are all connected with hair loss.  These would need to be evaluated by your doctor.


QUESTION 9: I recently had a highly sensitive C reactive Protein test done. My results were 36.6mg/l  in January and the repeat test results were 26.2mg/l. What does this mean? I had this test done in conjunction with other tests (hormonal tests) Should I check this out further? I have migraine headaches and the doctor said the increased levels of HS-CRP could be from this.  I need advice on what to do.

Answer:  An elevated HS-CRP indicates that you have increased inflammation present in your body indicating that your immune system has become overactive.  This could be caused by a host of factors including a viral, bacterial or fungal infection, food allergy or intolerance, heavy metal overload, free radical excess, insulin resistance associated with obesity and other possibilities.  All of these can be eliminated with the appropriate investigations, which can be performed by your doctor.

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